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- Title
First international consensus on the methodology of lymphangiogenesis quantification in solid human tumours.
- Authors
Van der Auwera, I; Cao, Y; Tille, J C; Pepper, M S; Jackson, D G; Fox, S B; Harris, A L; Dirix, L Y; Vermeulen, P B
- Abstract
The lymphatic system is the primary pathway of metastasis for most human cancers. Recent research efforts in studying lymphangiogenesis have suggested the existence of a relationship between lymphatic vessel density and patient survival. However, current methodology of lymphangiogenesis quantification is still characterised by high intra- and interobserver variability. For the amount of lymphatic vessels in a tumour to be a clinically useful parameter, a reliable quantification technique needs to be developed. With this consensus report, we therefore would like to initiate discussion on the standardisation of the immunohistochemical method for lymphangiogenesis assessment.
- Publication
British journal of cancer, 2006, Vol 95, Issue 12, p1611
- ISSN
0007-0920
- Publication type
Journal Article
- DOI
10.1038/sj.bjc.6603445