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- Title
Targeting insulin-like growth factor pathways.
- Authors
Yee, D
- Abstract
Some cancer cells depend on the function of specific molecules for their growth, survival, and metastatic potential. Targeting of these critical molecules has arguably been the best therapy for cancer as demonstrated by the success of tamoxifen and trastuzumab in breast cancer. This review will evaluate the type I IGF receptor (IGF-IR) as a potential target for cancer therapy. As new drugs come forward targeting this receptor system, several issues will need to be addressed in the early clinical trials using these agents.
- Publication
British journal of cancer, 2006, Vol 94, Issue 4, p465
- ISSN
0007-0920
- Publication type
Journal Article
- DOI
10.1038/sj.bjc.6602963