Works matching DE "TUMOR microenvironment"

Results: 5000

GPER1 is involved in shaping tumor immune microenvironment and its expression is decreased in NSCLC tumorigenesis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-15405-x

By:

Li, Zhenhua;
Xie, Chao;
Cui, Jingjing;
Xu, Hui;
Li, Dingbiao

Publication type:

Article

Glyoxalase 1 gene expression in various types of cancer cells immunopathology: a pan-cancer analysis study.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1610886

By:

Alaseem, Ali M.;
Aldali, Jehad A.;
Alasiri, Glowi;
Alhujaily, Muhanad;
AlHussaini, Khalid I.;
AlKhamees, Osama A.

Publication type:

Article

Fluorescence lifetime imaging microscopy approach reveals quantitative signatures for hepatocellular carcinoma diagnosis.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1598334

By:

Li, Lingyun;
Wang, Aoshan;
Liu, Xiongqing;
Wang, Ganlu;
Xu, Shanjie;
Li, Changjiang;
Wu, Wenzhong;
Zhang, Xiaoying;
He, Zhendan;
Qiu, Huiling;
Peng, Xiao;
Yan, Wei;
Qu, Junle

Publication type:

Article

Identification of a TIGIT-expressing CD8+ T cell subset as a potential prognostic biomarker in colorectal cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1626367

By:

Cao, Shouli;
Wang, Meidan;
Sun, Weiqiang;
Ma, Zhibin;
Yang, Kun;
Li, Ting;
Zhu, Xuedan;
Pei, Yang;
Pan, Mingyue;
Wang, Liqun;
Ding, Honglin

Publication type:

Article

Target neutrophil heterogeneity and plasticity in cancer.

Published in:

Journal of Hematology & Oncology, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13045-025-01731-0

By:

Feng, Ye;
Liu, Guang;
Li, Haiqing;
Cheng, Lin

Publication type:

Article

The molecular landscape of glioblastoma-associated epilepsy.

Published in:

Journal of Molecular Medicine, 2025, v. 103, n. 8, p. 923, doi. 10.1007/s00109-025-02567-4

By:

Scheffel, Thamiris Becker;
Diz, Fernando Mendonça;
Wieck, Andréa;
Begnini, Karine Rech;
da Costa, Jaderson Costa

Publication type:

Article

Unlocking the therapeutic potential of the STING signaling pathway in anti-tumor treatment.

Published in:

Clinical & Experimental Medicine, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10238-025-01838-1

By:

Li, Jinghui;
Yang, Haoqiang;
Zhu, Meiling;
Zhang, Pengyu;
Liu, Yang;
Niu, Yiting;
Zhou, Tao;
Li, Yanjun

Publication type:

Article

Integrative bulk RNA analysis unveils immune evasion mechanisms and predictive biomarkers of osimertinib resistance in non-small cell lung cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02529-9

By:

Shi, Ling;
Qiu, Feng;
Shi, Chao;
Zhang, Guohua;
Yu, Feng

Publication type:

Article

Unravelling inflammation-driven mechanisms in hepatocellular carcinoma: therapeutic targets and potential interventions.

Published in:

Egyptian Liver Journal, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s43066-025-00446-8

By:

Sen, Dhrubajyoti;
Bisht, Sonia;
Gupta, Sangeetha

Publication type:

Article

Advances in ORMDL Research in Malignant Tumors: A Review.

Published in:

OncoTargets & Therapy, 2025, v. 18, p. 821, doi. 10.2147/OTT.S537194

By:

Wang, Hao;
Yi, Zhongquan;
Yan, Song;
Wang, Yihao;
Zhang, Weisong;
Guo, Rongqi;
Li, Yangyang;
Wang, Rui;
Li, Heng;
Li, Xia;
Song, JianXiang

Publication type:

Article

GGTLC1 Is a Prognostic Biomarker in Renal Clear Cell Carcinoma.

Published in:

International Journal of Genomics, 2025, v. 2025, p. 1, doi. 10.1155/ijog/7524935

By:

Li, Shi;
Shi, Lijun;
Tao, Xiaofeng;
Yu, Guanghai;
Wang, Jianbo;
Sharma, Priyanka

Publication type:

Article

Harnessing intratumoral microbiota: new horizons in immune microenvironment and immunotherapy.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06916-2

By:

Zhang, Jinhe;
You, Zinan;
Li, Xinqiao;
Hu, Jinpeng;
Li, Jiamu;
Jing, Zhitao

Publication type:

Article

Nonhistone lactylation: A hub for tumour metabolic reprogramming and epigenetic regulation.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06813-8

By:

Zhang, Dawei;
Liang, Changming;
Wu, Chengwei;
Hawanga, Michael;
Wan, Senlin;
Xu, Lishuai;
Zhang, Xu;
Liu, Yongchun;
Hu, Fangshuai;
Wang, Mengyun;
Wang, Xiaoming;
Xu, Li;
Huang, Xiaoxu

Publication type:

Article

Radiocleavable rare-earth nanoactivators targeting over-expressed folate receptors induce mitochondrial dysfunction and remodel immune suppressive microenvironment in pancreatic cancer.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03657-8

By:

Gupta, Tanvi;
Wu, Shang-Rung;
Chang, Li-Chan;
Lin, Forn-Chia;
Shan, Yan-Shen;
Yeh, Chen-Sheng;
Su, Wen-Pin

Publication type:

Article

Targeting cytokine and chemokine signaling pathways for enhancing chemo-sensitivity in colorectal cancer.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02235-7

By:

Li, Shisen;
Xie, Mianjiao;
Du, Yongtao;
Tan, Zhaobang

Publication type:

Article

Multipath ROS Storm and Immune Activation via Sulfur Vacancy‐Optimized ZnIn2S4 Nanosheets for Piezocatalytic Tumor Therapy.

Published in:

Angewandte Chemie, 2025, v. 137, n. 33, p. 1, doi. 10.1002/ange.202507502

By:

Yang, Mingkai;
Ding, Binbin;
Ma, Xinyu;
Li, Jing;
Han, Di;
Liu, Sainan;
Liu, Zhendong;
Tan, Jia;
Chen, Hao;
Zheng, Pan;
Ma, Ping'an;
Lin, Jun

Publication type:

Article

ATP‐Inducible Receptor Oligomerization Enables Fine‐Tuning of T Cell Immunity.

Published in:

Angewandte Chemie, 2025, v. 137, n. 33, p. 1, doi. 10.1002/ange.202507125

By:

Li, Haoxiang;
Liang, Fuling;
Yu, Xin;
Sun, Shasha;
Li, Hui;
Jiang, Mingyan;
Jiang, Jian‐Hui;
He, Jianjun

Publication type:

Article

A Multifunctional Polyester Nanoplatform for the Synergistic Anticancer: Enhanced Photodynamic Therapy and Targeted Gene Silencing.

Published in:

Angewandte Chemie, 2025, v. 137, n. 33, p. 1, doi. 10.1002/ange.202505041

By:

Zhang, Xi;
Xu, De‐Zhong;
Zhao, Wen‐Jing;
Han, Xin‐Yue;
Lu, Zhong‐Lin;
Liu, Rui

Publication type:

Article

Piezo‐STING Agonists Enhance Tumor Penetration and Catalytic‐immunotherapy.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 32, p. 1, doi. 10.1002/adfm.202419032

By:

Li, Zhuo;
Yuan, Meng;
Liu, Hengrui;
Liu, Chang;
Zhang, Jinhui;
Guo, Yufei;
Li, Yifei;
He, Yuchu;
Zhang, Xuwu;
Gao, Dawei

Publication type:

Article

Integrated profiling of metaplastic breast cancer identifies putative master regulators of intratumoral heterogeneity.

Published in:

NPJ Breast Cancer, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41523-025-00807-x

By:

Feng, Yufan;
Xiong, Albert;
Mulay, Onkar;
Sokolova, Anna;
Lim, Malcolm;
Van Haeringen, Benjamin;
McGuire, Natasha;
de Luca, Xavier;
Simpson, Peter T.;
Nguyen, Quan;
Lakhani, Sunil R.;
McCart Reed, Amy E.

Publication type:

Article

Intratumoral microbiota: implications for cancer progression and treatment.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1551515

By:

Xie, Zehang;
Wu, Zhenguo;
Liu, Yan;
Gu, Yu;
Niu, Jiahao;
Lv, Kun

Publication type:

Article

Pyroptosis‐Mediated Antitumor Activity of Cinobufagin in Non‐Small Cell Lung Cancer.

Published in:

2025

By:

Chen, Ying;
Hu, Feng;
Lu, Jiahuan;
Zhu, Tengteng;
Zheng, Yajie;
Li, Yangyang;
Li, Jinwei;
Sheng, Kai;
Luo, Feng

Publication type:

Case Study

A Pan-Cancer Analysis of Natriuretic Peptide Receptor 3 (NPR3) with Clinical Cohort and in vitro Validation.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 9989, doi. 10.2147/JIR.S515347

By:

Liu, Yifan;
Liu, Jiangui;
Li, Yuanan;
Zhao, Zihui;
Lyu, Donghao;
Dong, Keqin;
Wei, Maodong;
Huang, Runzhi;
Lu, Bingnan;
Pan, Xiuwu

Publication type:

Article

Nanodrug-based modulation of platelet–leukocyte interactions in ovarian cancer: a new frontier in targeted therapy.

Published in:

Cancer Nanotechnology, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s12645-025-00340-3

By:

Naghinezhad, Jalal;
Moradpanah, Somayeh;
Khodakarim, Nastaran;
Hamblin, Michael R.;
Rezaeeyan, Hadi

Publication type:

Article

Low-liver-accumulation lipid nanoparticles enhance the efficacy and safety of HPV therapeutic tumor vaccines.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06924-2

By:

Wang, Xiaodie;
Tian, Zhidan;
Wang, Meng;
Cai, Xiaoru;
Yang, Shuyan;
Zeng, Jianyao;
Fang, Yuan;
Bai, Xuesen;
Wang, Pei;
Sun, Yan;
Guo, Chuanxin;
Liu, Tao;
Qian, Qijun

Publication type:

Article

Tumor-microenvironment triggered Mn-Gd based nanosystem for breast carcinoma suppression via synergistic radiotherapy and glutathione-depleting along with glucose oxidase combination enhanced Ros storm.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03636-z

By:

Su, Yonghui;
Guo, Dongqun;
Liang, Yinghao;
Meiheriban, Tuerdimaimaiti;
Chen, Siyu;
Tang, Qian;
Chen, Xiqian;
Huang, Yan;
Zhong, Jianqiao;
Liu, Zongjunlin

Publication type:

Article

Neurotransmitters: an emerging target for therapeutic resistance to tumor immune checkpoint inhibitors.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02413-8

By:

Yang, Jiyuan;
Wu, Yu;
Lv, Xinhui;
Liu, Sicong;
Yuan, Ziwen;
Chen, Yafang;
Ding, Xiangyu;
Li, Zhong;
Wang, Xudong

Publication type:

Article

CD24a knockout results in an enhanced macrophage- and CD8⁺ T cell-mediated anti-tumor immune responses in tumor microenvironment in a murine triple-negative breast cancer model.

Published in:

Journal of Biomedical Science, 2025, v. 32, n. 1, p. 1, doi. 10.1186/s12929-025-01165-3

By:

Chan, Shih-Hsuan;
Lin, Chin-Yu;
Tseng, Hsuan-Jung;
Wang, Lu-Hai

Publication type:

Article

Precision-cut tumor tissue slices, a novel tool to study the tumor microenvironment interactions with chimeric antigen receptor (CAR) T cells.

Published in:

PLoS ONE, 2025, v. 20, n. 8, p. 1, doi. 10.1371/journal.pone.0327322

By:

Durante, Valeria;
Wittwer, Alina;
Theek, Benjamin;
Martinez-Osuna, Manuel;
Donnadieu, Emmanuel;
Hardt, Olaf;
Eckardt, Dominik;
Bosio, Andreas;
Schallenberg, Sonja;
Herbel, Christoph

Publication type:

Article

Pannexin 1 and pannexin 3 differentially regulate the cancer cell properties of cutaneous squamous cell carcinoma.

Published in:

Journal of Physiology, 2025, v. 603, n. 15, p. 4409, doi. 10.1113/JP286172

By:

O'Donnell, Brooke L.;
Johnston, Danielle;
Bhatt, Ayushi;
Kardan, Zahra;
Stefan, Dan;
Bysice, Andrew;
Sayedyahossein, Samar;
Dagnino, Lina;
Cecchini, Matthew;
Loganathan, Sampath Kumar;
Roth, Kathryn;
Penuela, Silvia

Publication type:

Article

CAFs exosomal circFOXO1 promotes TNBC autophagy and radioresistance via miR-27a-3p/BNIP3 axis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-13876-6

By:

Xun, Xueqiong;
Hu, Huiyong;
Liu, Qing;
Su, Ruijun;
Ai, Jun

Publication type:

Article

Association of HLA-DRA expression with prognosis and tumor microenvironment in clear cell renal cell carcinoma.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-13665-1

By:

Qu, Shu-Xin;
Wang, Xiang;
Han, Wan-Ru;
Ge, Yu-Chen;
Feng, Bei;
Guo, Hai-Ying;
Sun, Xiao-Chen;
Wang, Kai;
Cui, Rui

Publication type:

Article

Prognostic significance of angiogenesis-associated molecules and Immunologic characteristic in elderly patients with acute myeloid leukemia.

Published in:

Annals of Hematology, 2025, v. 104, n. 7, p. 3681, doi. 10.1007/s00277-025-06454-3

By:

Chen, Can;
Huang, Yongfen;
Wang, Lingling;
Zhang, Linlin;
Lu, Jinbo;
Cheng, Yuexin;
Miao, Yuqing

Publication type:

Article

Targeting immune microenvironment in cervical cancer: current research and advances.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06896-3

By:

Zhang, Zhen;
Liu, Miao;
An, Yu;
Gao, Chongqing;
Wang, Tao;
Zhang, Zhi;
Zhang, Guixiang;
Li, Shuo;
Li, Wei;
Li, Mengjia;
Wang, Gangcheng

Publication type:

Article

Probiotic intervention alters immune gene expression and tumor characteristics in experimental breast cancer.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10873-w

By:

Barchelouei, Niloofar Khosrobaki;
Yazdi, Mohammad Hossein;
Haghighat, Setareh

Publication type:

Article

Advances and emerging trends in the tumor microenvironment of colorectal cancer liver metastasis: a bibliometric analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03292-7

By:

Wu, Qiong;
Zhao, Jie;
Sun, Zhongqi;
Jiang, Hao;
Qiao, Guanzhong;
Zhao, Kai;
Fan, Tingting;
Jiang, Huijie

Publication type:

Article

Targeting SPATS2 in lung adenocarcinoma: implications for prognosis and immune-based therapy.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03179-7

By:

Teng, Maorong;
Yan, Fangtao;
Shang, Jingping;
Sun, Xiaohua;
Wang, Yahui;
Shen, Jian

Publication type:

Article

Anti-PD-1 therapy for preventing recurrence and improving survival in hepatocellular carcinoma patients after hepatectomy.

Published in:

BMC Surgery, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12893-025-03117-y

By:

Zhao, Xiansheng;
Peng, Yong;
Hu, Airong;
Jiang, Suwen

Publication type:

Article

Machine learning-driven multi-omics analysis identifies a prognostic gene signature associated with programmed cell death and metabolism in hepatocellular carcinoma.

Published in:

Biological Procedures Online, 2025, v. 27, n. 1, p. 1, doi. 10.1186/s12575-025-00286-1

By:

Li, Xiang;
Yin, Donghao;
Geng, Jiahao;
Xu, Yanyu;
Xu, Zijing;
Yang, Xuemeng;
Li, Quanwei;
Shang, Zimeng;
Yang, Zhiyun;
Xu, Zhong;
Wang, Jiabo;
Zhang, Enxiang;
Song, Xinhua

Publication type:

Article

Spatial deciphering of the transcriptomic heterogeneity of tumor spread through air spaces in lung cancer.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1567527

By:

Wang, Wenhao;
Zhou, Wenhao;
Fan, Jingli;
Jiang, Tao;
Yang, Guang;
Song, Congcong;
Xu, Siwei;
Luo, Haitao;
Liu, Huining

Publication type:

Article

Heterotypic neutrophil-in-tumor structure: A novel pathological feature first discovered in the tissues of OPSCC.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2022.807597

By:

Fan, Jie;
Li, Peng;
Fang, Qigen;
Yang, Yang;
Zhang, He;
Du, Wei;
Liu, Shanting;
Luo, Ruihua

Publication type:

Article

NAP1L5 in acute myeloid leukemia: a prognostic biomarker and potential therapeutic target.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1617564

By:

Wang, Meng;
Xie, Zhibin;
Tan, Yuanyuan;
Zhou, Yan;
Zhang, Tingting;
Du, Yuqing;
Wu, Huan;
Zhou, Lili;
Ge, Jian

Publication type:

Article

Endosialin promotes vascular maturation by inhibiting Cyr61 expression in melanoma metastasis.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1528288

By:

Lu, Tong;
Song, Hongtao;
Zhao, Zhite;
He, Xinglin;
Xu, Chao;
Liu, Shaojie;
Qin, Weijun;
Yang, Bo;
Yang, Lijun

Publication type:

Article

Heterotypic neutrophil-in-tumor structure: A novel pathological feature first discovered in the tissues of OPSCC.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2022.807597

By:

Fan, Jie;
Li, Peng;
Fang, Qigen;
Yang, Yang;
Zhang, He;
Du, Wei;
Liu, Shanting;
Luo, Ruihua

Publication type:

Article

Correction: Myeloid Zinc Finger 1 : insights into its oncogenic potential, prognostic value, and impact on immune microenvironment across cancers.

Published in:

2025

By:

Tian, Wenze;
Yu, Chun;
Xu, Xin;
Li, Jiaqi;
Peng, Shuangfu;
Sun, Aijun;
Zhang, Shasha;
Jiang, Chao

Publication type:

Correction Notice

Harnessing innate immunity against glioblastoma microenvironment.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1648601

By:

Zhang, Wenbo;
Zhang, Wanhong;
Wu, Henghao;
Han, Xinsheng

Publication type:

Article

Correction: Crosstalk between the tumor immune microenvironment and metabolic reprogramming in pancreatic cancer: new frontiers in immunotherapy.

Published in:

2025

By:

Shi, Taijin;
Cui, Xiaoyan;
Wang, Junlin;
Liu, Guangqia;
Meng, Jiayin;
Zhang, Yingjie

Publication type:

Correction Notice

Research progress on mechanisms of tumor immune microenvironment and gastrointestinal resistance to immunotherapy: mini review.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1641518

By:

Zhang, Zheng;
Wu, Yangping

Publication type:

Article

Single-cell transcriptomic profiling reveals the heterogeneity of epithelial cells in lung adenocarcinoma lymph node metastasis and develops a prognostic signature.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1637625

By:

Mu, Qiuqiao;
Zhang, Han;
Shi, Ying;
Xue, Mengli;
Wang, Jingxian;
Ding, Yun;
Tan, Lin;
Yuan, Hui;
Li, Xin;
Sun, Daqiang

Publication type:

Article

Single-cell and spatial atlas of glioblastoma heterogeneity: characterizing the PCLAF + subtype and YEATS4 's oncogenic role.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1614549

By:

Ma, Siqi;
Sun, Yuwei;
Zheng, Shaowei;
Fu, Yilong;
Wang, Liangyu;
Liu, Dun;
Jiao, Henan;
Zhu, Xuqiang;
Li, Xueyuan;
Yan, Dongming;
Chen, Di;
Ye, Zi

Publication type:

Article