Your institution may have access to this item. Find your institution then sign in to continue.
Title
Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini.
Authors
Kirino, Yohei; Mourelatos, Zissimos
Abstract
Piwi-interacting RNAs (piRNAs) are a novel class of small RNAs that are expressed specifically and abundantly in male germ cells. Here we report that the 3' termini of piRNAs are 2'-O-methylated; this modification may have important implications for the biogenesis and function of piRNAs.