Works matching DE "UBIQUITINATION"

Results: 3912

Correction: Ube2v1-mediated ubiquitination and degradation of Sirt1 promotes metastasis of colorectal cancer by epigenetically suppressing autophagy.

Published in:

2025

By:

Shen, Tong;
Cai, Ling-Dong;
Liu, Yu-Hong;
Li, Shi;
Gan, Wen-Juan;
Li, Xiu-Ming;
Wang, Jing-Ru;
Guo, Peng-Da;
Zhou, Qun;
Lu, Xing-Xing;
Sun, Li-Na;
Li, Jian-Ming

Publication type:

Correction Notice

Proteome‐Wide Data Guides the Discovery of Lysine‐Targeting Covalent Inhibitors Using DNA‐Encoded Chemical Libraries.

Published in:

Angewandte Chemie, 2025, v. 137, n. 25, p. 1, doi. 10.1002/ange.202505581

By:

Wu, Xinyuan;
Li, Shunyao;
Liang, Ting;
Yu, Qing;
Zhang, Yiwei;
Liu, Jiaxiang;
Li, Kaige;
Liu, Zijian;
Cui, Mengqing;
Zhao, Yongchao;
Han, Xin;
Jin, Rui;
Tan, Minjia;
Chen, Xiao‐Hua;
Zhao, Yujun;
Zheng, Mingyue;
Sun, Yi;
Zhou, Lu;
Lu, Xiaojie

Publication type:

Article

Mechanism of KDM4A in Regulating Microglial Polarization in Ischemic Stroke.

Published in:

Applied Biochemistry & Biotechnology, 2025, v. 197, n. 6, p. 3871, doi. 10.1007/s12010-025-05207-2

By:

Du, Jingliang;
Liang, Xianyang;
Wang, Denghui;
Wang, Zhen;
Shen, Ruile

Publication type:

Article

ZNF432 suppresses endometrial cancer progression by promoting UPF1 ubiquitination and inducing apoptosis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02915-3

By:

Li, Xinjun;
Qi, Jie;
Xu, Ren;
Xu, Shuo;
Wang, Shengpu;
Wang, Chunxiao;
Zhao, Sufen

Publication type:

Article

Late‐Stage Intermolecular O‐Peptidylation Protocol Enabled by Sequential Acyl Transfer on Thiol‐Incorporated Threonine Followed by Desulfurization.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 33, p. 1, doi. 10.1002/chem.202501072

By:

Sato, Daiki;
Ota, Rika;
Shinozaki, Chiho;
Denda, Masaya;
Otaka, Akira

Publication type:

Article

Ubiquitin-specific protease 38 modulates atrial fibrillation susceptibility in chronic kidney disease via STRAP stabilization and activation of TGF-β/SMAD signaling.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01296-1

By:

Meng, Hong;
Qu, Zongze;
Xiao, Zheng;
Kong, Bin;
Yang, Hongjie;
Shuai, Wei;
Huang, He

Publication type:

Article

Hypoxia‐mediated high expression of TRIM15 promotes malignant progression of high‐grade serous ovarian cancer through activation of AKT signaling pathway by K63 ubiquitination.

Published in:

International Journal of Cancer, 2025, v. 156, n. 12, p. 2401, doi. 10.1002/ijc.35387

By:

Wei, Wei;
Zhang, Yang;
Li, Yibing;
Huang, Jiazhen;
Kang, Fuli;
Tan, Shuang;
Lin, Lin;
Lu, Xiaohang;
Wei, Heng;
Wang, Ning

Publication type:

Article

O-GlcNAcylation with ubiquitination stabilizes METTL3 to promoting HMGB1 degradation to inhibit ferroptosis and enhance gemcitabine resistance in pancreatic cancer.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01285-4

By:

Wang, Qiuhong;
Wei, Dong;
Li, Chunman;
Yang, Xiawei;
Su, Kun;
Wang, Tao;
Zou, Renchao;
Wang, Lianmin;
Cun, Dongyun;
Tang, Bo;
Wu, Tao

Publication type:

Article

Aging and diet alter the protein ubiquitylation landscape in the mouse brain.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60542-6

By:

Marino, Antonio;
Di Fraia, Domenico;
Panfilova, Diana;
Sahu, Amit Kumar;
Minetti, Alberto;
Omrani, Omid;
Cirri, Emilio;
Ori, Alessandro

Publication type:

Article

Commissureless acts as a substrate adapter in a conserved Nedd4 E3 ubiquitin ligase pathway to promote axon growth across the midline.

Published in:

eLife, 2025, p. 1

By:

Sullivan, Kelly G.;
Bashaw, Greg J.

Publication type:

Article

Sequence rules for a long SPOP-binding degron required for protein ubiquitylation.

Published in:

Biochemical Journal, 2025, v. 482, n. 10, p. 583, doi. 10.1042/BCJ20253041

By:

Makhlouf, Linda;
Mishra, Mukul;
Makhlouf, Hannah;
Manfield, Iain;
Busino, Luca;
Zeqiraj, Elton

Publication type:

Article

Identification and validation of a thirteen-gene signature based on ubiquitin related genes in cervical cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02459-6

By:

Ding, Wenxiu;
Liu, Shu;
Zhang, Huiai;
Ding, Hongxia;
Zhou, Shaobing;
Ye, Hongxun

Publication type:

Article

Studies on the functional role of UFMylation in cells (Review).

Published in:

Molecular Medicine Reports, 2025, v. 32, n. 1, p. N.PAG, doi. 10.3892/mmr.2025.13556

By:

Qin, Rong;
Tang, Yu;
Yuan, Yuhang;
Meng, Fangyu;
Zheng, Kepu;
Yang, Xingyu;
Zhao, Jiumei;
Yang, Chuanhua

Publication type:

Article

Functional Diversity of A-Type RING Ligases (ATL) Genes: Insights into the Crucial Roles of E3 Ubiquitin Ligases in Plant Biology.

Published in:

Journal of Plant Growth Regulation, 2025, v. 44, n. 5, p. 1827, doi. 10.1007/s00344-024-11547-w

By:

Sierra-Cacho, Daniel;
Méndez-Gómez, Manuel;
Aguilar-Hernández, Victor;
Guzmán, Plinio

Publication type:

Article

Brassinosteroid Signaling Dynamics: Ubiquitination-Dependent Regulation of Core Signaling Components.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4502, doi. 10.3390/ijms26104502

By:

Qiu, Riguang;
Zhou, Yan;
Mao, Juan

Publication type:

Article

Structural basis for the RING-catalyzed synthesis of K63-linked ubiquitin chains.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 8, p. 597, doi. 10.1038/nsmb.3052

By:

Branigan, Emma;
Plechanovová, Anna;
Jaffray, Ellis G;
Naismith, James H;
Hay, Ronald T

Publication type:

Article

K63 polyubiquitination is a new modulator of the oxidative stress response.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 2, p. 116, doi. 10.1038/nsmb.2955

By:

Silva, Gustavo M;
Finley, Daniel;
Vogel, Christine

Publication type:

Article

Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 6, p. 569, doi. 10.1038/nsmb.2833

By:

Kalb, Reinhard;
Latwiel, Sebastian;
Baymaz, H Irem;
Jansen, Pascal W T C;
Müller, Christoph W;
Vermeulen, Michiel;
Müller, Jürg

Publication type:

Article

Plant ubiquitin ligases as signaling hubs.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 293, doi. 10.1038/nsmb.2804

By:

Shabek, Nitzan;
Zheng, Ning

Publication type:

Article

The JAMM in the proteasome.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 346, doi. 10.1038/nsmb.2800

By:

Wauer, Tobias;
Komander, David

Publication type:

Article

Ubiquitin sets the timer: impacts on aging and longevity.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 290, doi. 10.1038/nsmb.2806

By:

Kevei, Éva;
Hoppe, Thorsten

Publication type:

Article

New insights into ubiquitin E3 ligase mechanism.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 301, doi. 10.1038/nsmb.2780

By:

Berndsen, Christopher E;
Wolberger, Cynthia

Publication type:

Article

Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 336, doi. 10.1038/nsmb.2787

By:

Klionsky, Daniel J;
Schulman, Brenda A

Publication type:

Article

Two-way communications between ubiquitin-like modifiers and DNA.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 317, doi. 10.1038/nsmb.2805

By:

Ulrich, Helle D

Publication type:

Article

Ubiquitin in inflammation: the right linkage makes all the difference.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 297, doi. 10.1038/nsmb.2808

By:

Corn, Jacob E;
Vucic, Domagoj

Publication type:

Article

Cleaning up in the endoplasmic reticulum: ubiquitin in charge.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 325, doi. 10.1038/nsmb.2793

By:

Christianson, John C;
Ye, Yihong

Publication type:

Article

Essential modifications.

Published in:: Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 289, doi. 10.1038/nsmb.2811
Publication type:: Article

Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 308, doi. 10.1038/nsmb.2792

By:

Mattiroli, Francesca;
Sixma, Titia K

Publication type:

Article

Centromeric histone H2B monoubiquitination promotes noncoding transcription and chromatin integrity.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 3, p. 236, doi. 10.1038/nsmb.2776

By:

Sadeghi, Laia;
Siggens, Lee;
Svensson, J Peter;
Ekwall, Karl

Publication type:

Article

JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1-mediated chromatin response to DNA breaks.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 12, p. 1425, doi. 10.1038/nsmb.2702

By:

Watanabe, Sugiko;
Watanabe, Kenji;
Akimov, Vyacheslav;
Bartkova, Jirina;
Blagoev, Blagoy;
Lukas, Jiri;
Bartek, Jiri

Publication type:

Article

Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 8, p. 982, doi. 10.1038/nsmb.2621

By:

Dou, Hao;
Buetow, Lori;
Sibbet, Gary J;
Cameron, Kenneth;
Huang, Danny T

Publication type:

Article

EMI1, a three-in-one ubiquitylation inhibitor.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 7, p. 773, doi. 10.1038/nsmb.2626

By:

Yamano, Hiroyuki

Publication type:

Article

Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 6, p. 696, doi. 10.1038/nsmb.2566

By:

Maspero, Elena;
Valentini, Eleonora;
Mari, Sara;
Cecatiello, Valentina;
Soffientini, Paolo;
Pasqualato, Sebastiano;
Polo, Simona

Publication type:

Article

Sequential primed kinases create a damage-responsive phosphodegron on Eco1.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 2, p. 194, doi. 10.1038/nsmb.2478

By:

Lyons, Nicholas A;
Fonslow, Bryan R;
Diedrich, Jolene K;
Yates, John R;
Morgan, David O

Publication type:

Article

Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 7, p. 2506, doi. 10.1002/chem.202004590

By:

Kim, Robbert Q.;
Misra, Mohit;
Gonzalez, Alexis;
Tomašković, Ines;
Shin, Donghyuk;
Schindelin, Hermann;
Filippov, Dmitri V.;
Ovaa, Huib;
Đikić, Ivan;
Heden van Noort, Gerbrand J.

Publication type:

Article

A Buchwald–Hartwig Protocol to Enable Rapid Linker Exploration of Cereblon E3‐Ligase PROTACs**.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 70, p. 16818, doi. 10.1002/chem.202003137

By:

Hayhow, Thomas G.;
Borrows, Rachel E. A.;
Diène, Coura R.;
Fairley, Gary;
Fallan, Charlene;
Fillery, Shaun M.;
Scott, James S.;
Watson, David W.

Publication type:

Article

Fluorescently Labelled ATP Analogues for Direct Monitoring of Ubiquitin Activation.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 28, p. 6279, doi. 10.1002/chem.202001091

By:

Hammler, Daniel;
Stuber, Katrin;
Offensperger, Fabian;
Scheffner, Martin;
Zumbusch, Andreas;
Marx, Andreas

Publication type:

Article

Modifying the Vicinity of the Isopeptide Bond To Reveal Differential Behavior of Ubiquitin Chains with Interacting Proteins: Organic Chemistry Applied to Synthetic Proteins.

Published in:

Angewandte Chemie, 2013, v. 125, n. 42, p. 11355, doi. 10.1002/ange.201306118

By:

Haj ‐ Yahya, Najat;
Haj ‐ Yahya, Mahmood;
Castañeda, Carlos A.;
Spasser, Liat;
Hemantha, Hosahalli P.;
Jbara, Muhammad;
Penner, Marlin;
Ciechanover, Aaron;
Fushman, David;
Brik, Ashraf

Publication type:

Article

Convergent Chemical Synthesis of Histone H2B Protein for the Site-Specific Ubiquitination at Lys34.

Published in:

Angewandte Chemie, 2013, v. 125, n. 31, p. 8217, doi. 10.1002/ange.201303844

By:

Siman, Peter;
Karthikeyan, Subramanian Vedhanarayanan;
Nikolov, Miroslav;
Fischle, Wolfgang;
Brik, Ashraf

Publication type:

Article

TRIM11 modulates sepsis progression by promoting HOXB9 ubiquitination and inducing the NF-κB signaling pathway.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-024-10212-5

By:

Gan, Jiaqi;
Zhang, Wei;
Pan, Fei;
Qiu, Zhiyun;
Chen, Xiaobing

Publication type:

Article

The Bre1/Rad6 machinery: writing the central histone ubiquitin mark on H2B and beyond.

Published in:

Chromosome Research, 2020, v. 28, n. 3/4, p. 247, doi. 10.1007/s10577-020-09640-3

By:

Deng, Zhi-Heng;
Ai, Hua-Song;
Lu, Cheng-Piao;
Li, Jia-Bin

Publication type:

Article

Antiproliferative activity exerted by tricyclohexylphosphanegold(I) n-mercaptobenzoate against MCF-7 and A2780 cell lines: the role of p53 signaling pathways.

Published in:

BioMetals, 2021, v. 34, n. 1, p. 141, doi. 10.1007/s10534-020-00269-7

By:

Ang, Kok Pian;
Chan, Pit Foong;
Hamid, Roslida Abd

Publication type:

Article

Hepatic and adipocyte cells respond differentially to iron overload, hypoxic and inflammatory challenge.

Published in:

BioMetals, 2012, v. 25, n. 4, p. 749, doi. 10.1007/s10534-012-9543-9

By:

Andrews, M.;
Arredondo, M.

Publication type:

Article

Triad3A attenuates pathological cardiac hypertrophy involving the augmentation of ubiquitination-mediated degradation of TLR4 and TLR9.

Published in:

Basic Research in Cardiology, 2020, v. 115, n. 2, p. 1, doi. 10.1007/s00395-020-0779-1

By:

Lu, Xia;
He, Yijie;
Tang, Chao;
Wang, Xiaoyang;
Que, Linli;
Zhu, Guoqing;
Liu, Li;
Ha, Tuanzhu;
Chen, Qi;
Li, Chuanfu;
Xu, Yong;
Li, Jiantao;
Li, Yuehua

Publication type:

Article

The post-translational modification of Fascin: impact on cell biology and its associations with inhibiting tumor metastasis.

Published in:

Amino Acids, 2022, v. 54, n. 12, p. 1541, doi. 10.1007/s00726-022-03193-x

By:

Nan-Li;
Zhang, Zhi-Da;
Li, Rong-Rong;
Chen, Jia-You;
Huang, Hong-Xin;
Cheng, Yin-Wei;
Xu, Li-Yan;
Li, En-Min

Publication type:

Article

Post-translational modifications in tumor-associated carbonic anhydrases.

Published in:

Amino Acids, 2022, v. 54, n. 4, p. 543, doi. 10.1007/s00726-021-03063-y

By:

Di Fiore, Anna;
Supuran, Claudiu T.;
Scaloni, Andrea;
De Simone, Giuseppina

Publication type:

Article

Enteral glutamine infusion modulates ubiquitination of heat shock proteins, Grp-75 and Apg-2, in the human duodenal mucosa.

Published in:

Amino Acids, 2014, v. 46, n. 4, p. 1059, doi. 10.1007/s00726-014-1670-x

By:

Bertrand, Julien;
Goichon, Alexis;
Chan, Philippe;
Azhar, Saida;
Lecleire, Stéphane;
Donnadieu, Nathalie;
Vaudry, David;
Cailleux, Anne-Françoise;
Déchelotte, Pierre;
Coëffier, Moïse

Publication type:

Article

RUBI: rapid proteomic-scale prediction of lysine ubiquitination and factors influencing predictor performance.

Published in:

Amino Acids, 2014, v. 46, n. 4, p. 853, doi. 10.1007/s00726-013-1645-3

By:

Walsh, Ian;
Domenico, Tomás;
Tosatto, Silvio

Publication type:

Article

Prediction of lysine ubiquitination with mRMR feature selection and analysis.

Published in:

Amino Acids, 2012, v. 42, n. 4, p. 1387, doi. 10.1007/s00726-011-0835-0

By:

Cai, Yudong;
Huang, Tao;
Hu, Lele;
Shi, Xiaohe;
Xie, Lu;
Li, Yixue

Publication type:

Article

Aurora A binds to the transactivation domain of c-Myc and recognizes the phosphorylated N-terminal degron motif.

Published in:

Biochemical Journal, 2025, v. 482, n. 8, p. 369, doi. 10.1042/BCJ20240726

By:

Nidhi Joshi;
Dunleavy, Katie M.;
Beel, Kaitlin M.;
Engel, Tiffany A.;
Thompson, Andrew R.;
John, Felix L.;
Thomas, David D.;
Levinson, Nicholas M.

Publication type:

Article