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- Title
Regulation of nucleosome dynamics by histone modifications.
- Authors
Zentner, Gabriel E; Henikoff, Steven
- Abstract
Chromatin is a dynamic structure that must respond to myriad stimuli to regulate access to DNA, and chemical modification of histones is a major means by which the cell modulates nucleosome mobility and turnover. Histone modifications are linked to essentially every cellular process requiring DNA access, including transcription, replication and repair. Here we consider properties of the major types of histone modification in the context of their associated biological processes to view them in light of the cellular mechanisms that regulate nucleosome dynamics.
- Publication
Nature structural & molecular biology, 2013, Vol 20, Issue 3, p259
- ISSN
1545-9985
- Publication type
Journal Article
- DOI
10.1038/nsmb.2470