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- Title
Translation drives mRNA quality control.
- Authors
Shoemaker, Christopher J; Green, Rachel
- Abstract
There are three predominant forms of co-translational mRNA surveillance: nonsense-mediated decay (NMD), no-go decay (NGD) and nonstop decay (NSD). Although discussion of these pathways often focuses on mRNA fate, there is growing consensus that there are other important outcomes of these processes that must be simultaneously considered. Here, we seek to highlight similarities between NMD, NGD and NSD and their probable origins on the ribosome during translation.
- Publication
Nature structural & molecular biology, 2012, Vol 19, Issue 6, p594
- ISSN
1545-9985
- Publication type
Journal Article
- DOI
10.1038/nsmb.2301