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- Title
New neurons for 'survival of the fittest'.
- Authors
Kempermann, Gerd
- Abstract
Adult neurogenesis is often considered an archaic trait that has undergone a 'phylogenetic reduction' from amphibian ancestors to humans. However, adult neurogenesis in the hippocampal dentate gyrus might actually be a late-evolved trait. In non-mammals, adult hippocampal neurogenesis is not restricted to the equivalents of the dentate gyrus, which also show different connectivity and functionality compared to their mammalian counterpart. Moving actively in a changing world and dealing with novelty and complexity regulate adult neurogenesis. New neurons might thus provide the cognitive adaptability to conquer ecological niches rich with challenging stimuli.
- Publication
Nature reviews. Neuroscience, 2012, Vol 13, Issue 10, p727
- ISSN
1471-0048
- Publication type
Journal Article
- DOI
10.1038/nrn3319