We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Cell-cycle control and cortical development.
- Authors
Dehay, Colette; Kennedy, Henry
- Abstract
The spatio-temporal timing of the last round of mitosis, followed by the migration of neuroblasts to the cortical plate leads to the formation of the six-layered cortex that is subdivided into functionally defined cortical areas. Whereas many of the cellular and molecular mechanisms have been established in rodents, there are a number of unique features that require further elucidation in primates. Recent findings both in rodents and in primates indicate that regulation of the cell cycle, specifically of the G1 phase has a crucial role in controlling area-specific rates of neuron production and the generation of cytoarchitectonic maps.
- Publication
Nature reviews. Neuroscience, 2007, Vol 8, Issue 6, p438
- ISSN
1471-003X
- Publication type
Journal Article
- DOI
10.1038/nrn2097