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- Title
Opinion: Statins-a cure-all for the brain?
- Authors
Menge, Til; Hartung, Hans-Peter; Stüve, Olaf
- Abstract
'Statins' are 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors-oral cholesterol-lowering drugs that are used to treat hypercholesterolaemia. It is widely accepted that statins have anti-inflammatory effects that are independent of their ability to lower cholesterol. Animal studies and observational clinical studies have indicated that statins might also be effective in treating certain neurological diseases-in particular, multiple sclerosis, Alzheimer's disease and ischaemic stroke. At present, however, results from ongoing prospective, randomized clinical trials are not available.
- Publication
Nature Reviews Neuroscience, 2005, Vol 6, Issue 4, p325
- ISSN
1471-003X
- Publication type
Academic Journal
- DOI
10.1038/nrn1652