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Title: West Nile virus infection and immunity.
Authors: Suthar, Mehul S.; Diamond, Michael S.; Gale Jr, Michael
Abstract: West Nile virus (WNV) is an emerging neurotropic flavivirus that is transmitted to humans through the bite of an infected mosquito. WNV has disseminated broadly in the Western hemisphere and now poses a significant public health risk. The continuing spread of WNV, combined with the lack of specific therapeutics or vaccines to combat or prevent infection, imparts a pressing need to identify the viral and host processes that control the outcome of and immunity to WNV infection. Here, we provide an overview of recent research that has revealed the virus-host interface controlling WNV infection and immunity.
Subjects: WEST Nile virus; FLAVIVIRAL diseases; MOSQUITO vectors; INFECTION prevention; IMMUNITY; MEDICAL care; INSECTS
Publication: Nature Reviews Microbiology, 2013, Vol 11, Issue 2, p115
ISSN: 1740-1526
Publication type: Academic Journal
DOI: 10.1038/nrmicro2950

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West Nile virus infection and immunity.