We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
From the regulation of peptidoglycan synthesis to bacterial growth and morphology.
- Authors
Typas, Athanasios; Banzhaf, Manuel; Gross, Carol A.; Vollmer, Waldemar
- Abstract
How bacteria grow and divide while retaining a defined shape is a fundamental question in microbiology, but technological advances are now driving a new understanding of how the shape-maintaining bacterial peptidoglycan sacculus grows. In this Review, we highlight the relationship between peptidoglycan synthesis complexes and cytoskeletal elements, as well as recent evidence that peptidoglycan growth is regulated from outside the sacculus in Gram-negative bacteria. We also discuss how growth of the sacculus is sensitive to mechanical force and nutritional status, and describe the roles of peptidoglycan hydrolases in generating cell shape and of D-amino acids in sacculus remodelling.
- Publication
Nature Reviews Microbiology, 2012, Vol 10, Issue 2, p123
- ISSN
1740-1526
- Publication type
Academic Journal
- DOI
10.1038/nrmicro2677