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- Title
Chronic and acute infection of the gall bladder by Salmonella Typhi: understanding the carrier state.
- Authors
Gonzalez-Escobedo, Geoffrey; Marshall, Joanna M; Gunn, John S
- Abstract
Despite major treatment and prevention efforts, millions of new typhoid infections occur worldwide each year. For a subset of infected individuals, Salmonella enterica subsp. enterica serovar Typhi colonizes the gall bladder and remains there long after symptoms subside, serving as a reservoir for the further spread of the disease. In this Progress article, we explore recent advances in our understanding of the mechanisms by which Salmonella spp.--predominantly S. Typhi--colonize and persist in the human gall bladder.
- Publication
Nature reviews. Microbiology, 2011, Vol 9, Issue 1, p9
- ISSN
1740-1534
- Publication type
Journal Article
- DOI
10.1038/nrmicro2490