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- Title
Genetic control of Candida albicans biofilm development.
- Authors
Finkel, Jonathan S; Mitchell, Aaron P
- Abstract
Candida species cause frequent infections owing to their ability to form biofilms - surface-associated microbial communities - primarily on implanted medical devices. Increasingly, mechanistic studies have identified the gene products that participate directly in the development of Candida albicans biofilms, as well as the regulatory circuitry and networks that control their expression and activity. These studies have uncovered new mechanisms and signals that govern C. albicans biofilm development and associated drug resistance, thus providing biological insight and therapeutic foresight.
- Publication
Nature reviews. Microbiology, 2011, Vol 9, Issue 2, p109
- ISSN
1740-1534
- Publication type
Journal Article
- DOI
10.1038/nrmicro2475