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- Title
H-NS, the genome sentinel.
- Authors
Dorman, Charles J
- Abstract
Two recent reports have indicated that the H-NS protein in Salmonella enterica serovar Typhimurium has a key role in selectively silencing the transcription of large numbers of horizontally acquired AT-rich genes, including those that make up its major pathogenicity islands. Broadly similar conclusions have emerged from a study of H-NS binding to DNA in Escherichia coli. How do these findings affect our view of H-NS and its ability to influence bacterial evolution?
- Publication
Nature reviews. Microbiology, 2007, Vol 5, Issue 2, p157
- ISSN
1740-1534
- Publication type
Journal Article
- DOI
10.1038/nrmicro1598