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- Title
Messenger-RNA-binding proteins and the messages they carry.
- Authors
Dreyfuss, Gideon; Kim, V Narry; Kataoka, Naoyuki
- Abstract
From sites of transcription in the nucleus to the outreaches of the cytoplasm, messenger RNAs are associated with RNA-binding proteins. These proteins influence pre-mRNA processing as well as the transport, localization, translation and stability of mRNAs. Recent discoveries have shown that one group of these proteins marks exon exon junctions and has a role in mRNA export. These proteins communicate crucial information to the translation machinery for the surveillance of nonsense mutations and for mRNA localization and translation.
- Publication
Nature reviews. Molecular cell biology, 2002, Vol 3, Issue 3, p195
- ISSN
1471-0072
- Publication type
Journal Article
- DOI
10.1038/nrm760