We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
TRANSCRIPTION: SIBLING RIVALRY IN THE E2F FAMILY.
- Authors
Trimarchi, Jeffrey M.; Lees, Jacqueline A.
- Abstract
The E2F transcription factor family determines whether or not a cell will divide by controlling the expression of key cell-cycle regulators. The individual E2Fs can be divided into distinct subgroups that act in direct opposition to one another to promote either cellular proliferation or cell-cycle exit and terminal differentiation. What is the underlying molecular basis of this 'push-me?pull-you' regulation, and what are its biological consequences?
- Publication
Nature Reviews Molecular Cell Biology, 2002, Vol 3, Issue 1, p11
- ISSN
1471-0072
- Publication type
Academic Journal
- DOI
10.1038/nrm714