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- Title
Clocks not winding down: unravelling circadian networks.
- Authors
Zhang, Eric E; Kay, Steve A
- Abstract
An intrinsic clock enables an organism to anticipate environmental changes and use energy sources more efficiently, thereby conferring an adaptive advantage. Having an intrinsic clock to orchestrate rhythms is also important for human health. The use of systems biology approaches has advanced our understanding of mechanistic features of circadian oscillators over the past decade. The field is now in a position to develop a multiscale view of circadian systems, from the molecular level to the intact organism, and to apply this information for the development of new therapeutic strategies or for enhancing agricultural productivity in crops.
- Publication
Nature reviews. Molecular cell biology, 2010, Vol 11, Issue 11, p764
- ISSN
1471-0080
- Publication type
Journal Article
- DOI
10.1038/nrm2995