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- Title
The evolving understanding of COPI vesicle formation.
- Authors
Hsu, Victor W; Lee, Stella Y; Yang, Jia-Shu
- Abstract
The coat protein I (COPI) complex is considered to be one of the best-characterized coat complexes. Studies on how it functions in vesicle formation have provided seminal contributions to the general paradigm in vesicular transport that the ADP-ribosylation factor (ARF) small GTPases are key regulators of coat complexes. Here, we discuss emerging evidence that suggests the need to revise some long-held views on how COPI vesicle formation is achieved.
- Publication
Nature reviews. Molecular cell biology, 2009, Vol 10, Issue 5, p360
- ISSN
1471-0080
- Publication type
Review
- DOI
10.1038/nrm2663