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- Title
The promise of human induced pluripotent stem cells for research and therapy.
- Authors
Nishikawa, Shin-ichi; Goldstein, Robert A; Nierras, Concepcion R
- Abstract
Induced pluripotent stem (iPS) cells are human somatic cells that have been reprogrammed to a pluripotent state. There are several hurdles to be overcome before iPS cells can be considered as a potential patient-specific cell therapy, and it will be crucial to characterize the developmental potential of human iPS cell lines. As a research tool, iPS-cell technology provides opportunities to study normal development and to understand reprogramming. iPS cells can have an immediate impact as models for human diseases, including cancer
- Publication
Nature reviews. Molecular cell biology, 2008, Vol 9, Issue 9, p725
- ISSN
1471-0080
- Publication type
Journal Article
- DOI
10.1038/nrm2466