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- Title
Highway to the inner nuclear membrane: rules for the road.
- Authors
Lusk, C Patrick; Blobel, Günter; King, Megan C
- Abstract
To enter the nucleus a protein must be chaperoned by a transport factor through the nuclear pore complex or it must be small enough to pass through by diffusion. Although these principles have long described the nuclear import of soluble proteins, recent evidence indicates that they also apply to the import of integral inner nuclear membrane proteins. Here we develop a set of rules that might govern the transport of proteins to the inner nuclear membrane.
- Publication
Nature reviews. Molecular cell biology, 2007, Vol 8, Issue 5, p414
- ISSN
1471-0072
- Publication type
Journal Article
- DOI
10.1038/nrm2165