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- Title
Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs.
- Authors
Matera, A Gregory; Terns, Rebecca M; Terns, Michael P
- Abstract
Recent advances have fuelled rapid growth in our appreciation of the tremendous number, diversity and biological importance of non-coding (nc)RNAs. Because ncRNAs typically function as ribonucleoprotein (RNP) complexes and not as naked RNAs, understanding their biogenesis is crucial to comprehending their regulation and function. The small nuclear and small nucleolar RNPs are two well studied classes of ncRNPs with elaborate assembly and trafficking pathways that provide paradigms for understanding the biogenesis of other ncRNPs.
- Publication
Nature reviews. Molecular cell biology, 2007, Vol 8, Issue 3, p209
- ISSN
1471-0072
- Publication type
Review
- DOI
10.1038/nrm2124