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- Title
Linking data to models: data regression.
- Authors
Jaqaman, Khuloud; Danuser, Gaudenz
- Abstract
Mathematical models are an essential tool in systems biology, linking the behaviour of a system to the interactions between its components. Parameters in empirical mathematical models must be determined using experimental data, a process called regression. Because experimental data are noisy and incomplete, diagnostics that test the structural identifiability and validity of models and the significance and determinability of their parameters are needed to ensure that the proposed models are supported by the available data.
- Publication
Nature reviews. Molecular cell biology, 2006, Vol 7, Issue 11, p813
- ISSN
1471-0072
- Publication type
Review
- DOI
10.1038/nrm2030