We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Genome-wide patterns of histone modifications in yeast.
- Authors
Millar, Catherine B; Grunstein, Michael
- Abstract
Post-translational histone modifications and histone variants generate complexity in chromatin to enable the many functions of the chromosome. Recent studies have mapped histone modifications across the Saccharomyces cerevisiae genome. These experiments describe how combinations of modified and unmodified states relate to each other and particularly to chromosomal landmarks that include heterochromatin, subtelomeric chromatin, centromeres, origins of replication, promoters and coding regions. Such patterns might be important for the regulation of heterochromatin-mediated silencing, chromosome segregation, DNA replication and gene expression.
- Publication
Nature reviews. Molecular cell biology, 2006, Vol 7, Issue 9, p657
- ISSN
1471-0072
- Publication type
Journal Article
- DOI
10.1038/nrm1986