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- Title
Arp2/3 and SCAR: plants move to the fore.
- Authors
Deeks, Michael J; Hussey, Patrick J
- Abstract
The actin-nucleating Arp2/3 complex is essential for life in yeast and animals, but not in plants, in which mutants of Arp2/3 complex components show relatively minor developmental abnormalities. Animal cells control the activity of the Arp2/3 complex through the suppressor of cyclic AMP receptor (SCAR) complex to achieve cell motility. Amazingly, plants have also retained the SCAR cell-motility pathway, and now provide a unique model for the study of new aspects of SCAR function in the absence of cell motility.
- Publication
Nature reviews. Molecular cell biology, 2005, Vol 6, Issue 12, p954
- ISSN
1471-0072
- Publication type
Journal Article
- DOI
10.1038/nrm1765