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- Title
Plants, symbiosis and parasites: a calcium signalling connection.
- Authors
Harper, Jeffrey F; Harmon, Alice
- Abstract
A unique family of protein kinases has evolved with regulatory domains containing sequences that are related to Ca(2+)-binding EF-hands. In this family, the archetypal Ca(2+)-dependent protein kinases (CDPKs) have been found in plants and some protists, including the malarial parasite, Plasmodium falciparum. Recent genetic evidence has revealed isoform-specific functions for a CDPK that is essential for Plasmodium berghei gametogenesis, and for a related chimeric Ca(2+) and calmodulin-dependent protein kinase (CCaMK) that is essential to the formation of symbiotic nitrogen-fixing nodules in plants. In Arabidopsis thaliana, the analysis of 42 isoforms of CDPK and related kinases is expected to delineate Ca(2+) signalling pathways in all aspects of plant biology.
- Publication
Nature reviews. Molecular cell biology, 2005, Vol 6, Issue 7, p555
- ISSN
1471-0072
- Publication type
Journal Article
- DOI
10.1038/nrm1679