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- Title
MicroRNA biogenesis: coordinated cropping and dicing.
- Authors
Kim, V Narry
- Abstract
The recent discovery of microRNAs (miRNAs) took many by surprise because of their unorthodox features and widespread functions. These tiny, approximately 22-nucleotide, RNAs control several pathways including developmental timing, haematopoiesis, organogenesis, apoptosis, cell proliferation and possibly even tumorigenesis. Among the most pressing questions regarding this unusual class of regulatory miRNA-encoding genes is how miRNAs are produced in cells and how the genes themselves are controlled by various regulatory networks.
- Publication
Nature reviews. Molecular cell biology, 2005, Vol 6, Issue 5, p376
- ISSN
1471-0072
- Publication type
Journal Article
- DOI
10.1038/nrm1644