We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Organization of vesicular trafficking in epithelia.
- Authors
Rodriguez-Boulan, Enrique; Kreitzer, Geri; Müsch, Anne
- Abstract
Experiments using mammalian epithelial cell lines have elucidated biosynthetic and recycling pathways for apical and basolateral plasma-membrane proteins, and have identified components that guide apical and basolateral proteins along these pathways. These components include apical and basolateral sorting signals, adaptors for basolateral signals, and docking and fusion proteins for vesicular trafficking. Recent live-cell-imaging studies provide a real-time view of sorting processes in epithelial cells, including key roles for actin, microtubules and motors in the organization of post-Golgi trafficking.
- Publication
Nature reviews. Molecular cell biology, 2005, Vol 6, Issue 3, p233
- ISSN
1471-0072
- Publication type
Journal Article
- DOI
10.1038/nrm1593