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- Title
Intermediate filaments mediate cytoskeletal crosstalk.
- Authors
Chang, Lynne; Goldman, Robert D
- Abstract
Intermediate filaments, actin-containing microfilaments and microtubules are the three main cytoskeletal systems of vertebrate and many invertebrate cells. Although these systems are composed of distinctly different proteins, they are in constant and intimate communication with one another. Understanding the molecular basis of this cytoskeletal crosstalk is essential for determining the mechanisms that underlie many cell-biological phenomena. Recent studies have revealed that intermediate filaments and their associated proteins are important components in mediating this crosstalk.
- Publication
Nature reviews. Molecular cell biology, 2004, Vol 5, Issue 8, p601
- ISSN
1471-0072
- Publication type
Journal Article
- DOI
10.1038/nrm1438