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- Title
Trefoil factors: initiators of mucosal healing.
- Authors
Taupin, Douglas; Podolsky, Daniel K
- Abstract
Maintaining the integrity of the gastrointestinal tract, despite the continual presence of microbial flora and injurious agents, is essential. Epithelial continuity depends on a family of small, yet abundant, secreted proteins--the trefoil factors (TFFs). TFFs protect mucous epithelia from a range of insults and contribute to mucosal repair, although the signalling events that mediate these responses are only partially understood.
- Publication
Nature reviews. Molecular cell biology, 2003, Vol 4, Issue 9, p721
- ISSN
1471-0072
- Publication type
Journal Article
- DOI
10.1038/nrm1203