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- Title
Immunology of hepatitis B virus and hepatitis C virus infection.
- Authors
Rehermann, Barbara; Nascimbeni, Michelina
- Abstract
More than 500 million people worldwide are persistently infected with the hepatitis B virus (HBV) and/or hepatitis C virus (HCV) and are at risk of developing chronic liver disease, cirrhosis and hepatocellular carcinoma. Despite many common features in the pathogenesis of HBV- and HCV-related liver disease, these viruses markedly differ in their virological properties and in their immune escape and survival strategies. This review assesses recent advances in our understanding of viral hepatitis, contrasts mechanisms of virus-host interaction in acute hepatitis B and hepatitis C, and outlines areas for future studies.
- Publication
Nature reviews. Immunology, 2005, Vol 5, Issue 3, p215
- ISSN
1474-1733
- Publication type
Journal Article
- DOI
10.1038/nri1573