We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Long non-coding RNAs: insights into functions.
- Authors
Mercer, Tim R; Dinger, Marcel E; Mattick, John S
- Abstract
In mammals and other eukaryotes most of the genome is transcribed in a developmentally regulated manner to produce large numbers of long non-coding RNAs (ncRNAs). Here we review the rapidly advancing field of long ncRNAs, describing their conservation, their organization in the genome and their roles in gene regulation. We also consider the medical implications, and the emerging recognition that any transcript, regardless of coding potential, can have an intrinsic function as an RNA.
- Publication
Nature reviews. Genetics, 2009, Vol 10, Issue 3, p155
- ISSN
1471-0064
- Publication type
Journal Article
- DOI
10.1038/nrg2521