We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The evolution of hierarchical gene regulatory networks.
- Authors
Erwin, Douglas H; Davidson, Eric H
- Abstract
Comparative developmental evidence indicates that reorganizations in developmental gene regulatory networks (GRNs) underlie evolutionary changes in animal morphology, including body plans. We argue here that the nature of the evolutionary alterations that arise from regulatory changes depends on the hierarchical position of the change within a GRN. This concept cannot be accomodated by microevolutionary nor macroevolutionary theory. It will soon be possible to investigate these ideas experimentally, by assessing the effects of GRN changes on morphological evolution.
- Publication
Nature reviews. Genetics, 2009, Vol 10, Issue 2, p141
- ISSN
1471-0064
- Publication type
Journal Article
- DOI
10.1038/nrg2499