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- Title
Genetic linkage and association analyses for trait mapping in Plasmodium falciparum.
- Authors
Xinzhuan Su; Hayton, Karen; Wellems, Thomas E.
- Abstract
Genetic studies of Plasmodium falciparum laboratory crosses and field isolates have produced valuable insights into determinants of drug responses, antigenic variation, disease virulence, cellular development and population structures of these virulent human malaria parasites. Full-genome sequences and high-resolution haplotype maps of SNPs and microsatellites are now available for all 14 parasite chromosomes. Rapidly increasing genetic and genomic information on Plasmodium parasites, mosquitoes and humans will combine as a rich resource for new advances in our understanding of malaria, its transmission and its manifestations of disease.
- Publication
Nature Reviews Genetics, 2007, Vol 8, Issue 7, p497
- ISSN
1471-0056
- Publication type
Academic Journal
- DOI
10.1038/nrg2126