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- Title
The power of the 3' UTR: translational control and development.
- Authors
Kuersten, Scott; Goodwin, Elizabeth B
- Abstract
Many crucial decisions, such as the location and timing of cell division, cell-fate determination, and embryonic axes establishment, are made in the early embryo, a time in development when there is often little or no transcription. For this reason, the control of variation in gene expression in the early embryo often relies on post-transcriptional control of maternal genes. Although the early embryo is rife with translational control, controlling mRNA activity is also important in other developmental processes, such as stem-cell proliferation, sex determination, neurogenesis and erythropoiesis.
- Publication
Nature reviews. Genetics, 2003, Vol 4, Issue 8, p626
- ISSN
1471-0056
- Publication type
Journal Article
- DOI
10.1038/nrg1125