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- Title
NF-kappaB in cancer: from innocent bystander to major culprit.
- Authors
Karin, Michael; Cao, Yixue; Greten, Florian R; Li, Zhi-Wei
- Abstract
Nuclear factor of kappaB (NF-kappaB) is a sequence-specific transcription factor that is known to be involved in the inflammatory and innate immune responses. Although the importance of NF-KB in immunity is undisputed, recent evidence indicates that NF-kappaB and the signalling pathways that are involved in its activation are also important for tumour development. NF-kappaB should therefore receive as much attention from cancer researchers as it has already from immunologists.
- Publication
Nature reviews. Cancer, 2002, Vol 2, Issue 4, p301
- ISSN
1474-175X
- Publication type
Journal Article
- DOI
10.1038/nrc780