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Title
AP-1: A DOUBLE-EDGED SWORD IN TUMORIGENESIS.
Abstract
Focuses on the molecular mechanisms that regulate the oncogenic and anti-oncogenic effects of activator protein 1 (AP-1) in tumorigenesis. Function of the AP-1 proteins in tumorigenesis; Behavior of Jun and Fos proteins in mice; Details of the regulation of AP-1 activity that occurs at different levels; Significance of the discovery of some AP-1 proteins' anti-oncogenic functions.