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- Title
Bypassing V1: a direct geniculate input to area MT.
- Authors
Sincich, Lawrence C; Park, Ken F; Wohlgemuth, Melville J; Horton, Jonathan C
- Abstract
Thalamic nuclei are thought to funnel sensory information to the brain's primary cortical areas, which in turn transmit signals afresh to higher cortical areas. Here we describe a direct projection in the macaque monkey from the lateral geniculate nucleus (LGN) to the motion-selective middle temporal area (MTor V5), a cortical area not previously considered 'primary'. The constituent neurons are mostly koniocellular, send virtually no collateral axons to primary visual cortex (V1) and equal about 10% of the V1 population innervating MT. This pathway could explain the persistence of motion sensitivity in subjects following injury to V1, suggesting more generally that residual perception after damage in a primary area may arise from sparse thalamic input to 'secondary' cortical areas.
- Publication
Nature neuroscience, 2004, Vol 7, Issue 10, p1123
- ISSN
1097-6256
- Publication type
Journal Article
- DOI
10.1038/nn1318