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- Title
Reversible switching between epigenetic states in honeybee behavioral subcastes.
- Authors
Herb, Brian R; Wolschin, Florian; Hansen, Kasper D; Aryee, Martin J; Langmead, Ben; Irizarry, Rafael; Amdam, Gro V; Feinberg, Andrew P
- Abstract
In honeybee societies, distinct caste phenotypes are created from the same genotype, suggesting a role for epigenetics in deriving these behaviorally different phenotypes. We found no differences in DNA methylation between irreversible worker and queen castes, but substantial differences between nurses and forager subcastes. Reverting foragers back to nurses reestablished methylation levels for a majority of genes and provides, to the best of our knowledge, the first evidence in any organism of reversible epigenetic changes associated with behavior.
- Publication
Nature neuroscience, 2012, Vol 15, Issue 10, p1371
- ISSN
1546-1726
- Publication type
Journal Article
- DOI
10.1038/nn.3218