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- Title
Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset.
- Authors
Tritsch, Nicolas X; Rodríguez-Contreras, Adrián; Crins, Tom T H; Wang, Han Chin; Borst, J Gerard G; Bergles, Dwight E
- Abstract
We found rat central auditory neurons to fire action potentials in a precise sequence of mini-bursts before the age of hearing onset. This stereotyped pattern was initiated by hair cells in the cochlea, which trigger brief bursts of action potentials in auditory neurons each time they fire a Ca2+ spike. By generating theta-like activity, hair cells may limit the influence of synaptic depression in developing auditory circuits and promote consolidation of synapses.
- Publication
Nature neuroscience, 2010, Vol 13, Issue 9, p1050
- ISSN
1546-1726
- Publication type
Journal Article
- DOI
10.1038/nn.2604