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- Title
Beyond extinction: erasing human fear responses and preventing the return of fear.
- Authors
Kindt, Merel; Soeter, Marieke; Vervliet, Bram
- Abstract
Animal studies have shown that fear memories can change when recalled, a process referred to as reconsolidation. We found that oral administration of the beta-adrenergic receptor antagonist propranolol before memory reactivation in humans erased the behavioral expression of the fear memory 24 h later and prevented the return of fear. Disrupting the reconsolidation of fear memory opens up new avenues for providing a long-term cure for patients with emotional disorders.
- Publication
Nature neuroscience, 2009, Vol 12, Issue 3, p256
- ISSN
1546-1726
- Publication type
Journal Article
- DOI
10.1038/nn.2271