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- Title
Quantifying the local resolution of cryo-EM density maps.
- Authors
Kucukelbir, Alp; Sigworth, Fred J; Tagare, Hemant D
- Abstract
We propose a definition of local resolution for three-dimensional electron cryo-microscopy (cryo-EM) density maps that uses local sinusoidal features. Our algorithm has no free parameters and is applicable to other imaging modalities, including tomography. By evaluating the local resolution of single-particle reconstructions and subtomogram averages for four example data sets, we report variable resolution across a 4- to 40-Å range.
- Publication
Nature methods, 2014, Vol 11, Issue 1, p63
- ISSN
1548-7105
- Publication type
Journal Article
- DOI
10.1038/nmeth.2727