We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
An image analysis toolbox for high-throughput C. elegans assays.
- Authors
Wählby, Carolina; Kamentsky, Lee; Liu, Zihan H; Riklin-Raviv, Tammy; Conery, Annie L; O'Rourke, Eyleen J; Sokolnicki, Katherine L; Visvikis, Orane; Ljosa, Vebjorn; Irazoqui, Javier E; Golland, Polina; Ruvkun, Gary; Ausubel, Frederick M; Carpenter, Anne E
- Abstract
We present a toolbox for high-throughput screening of image-based Caenorhabditis elegans phenotypes. The image analysis algorithms measure morphological phenotypes in individual worms and are effective for a variety of assays and imaging systems. This WormToolbox is available through the open-source CellProfiler project and enables objective scoring of whole-worm high-throughput image-based assays of C. elegans for the study of diverse biological pathways that are relevant to human disease.
- Publication
Nature methods, 2012, Vol 9, Issue 7, p714
- ISSN
1548-7105
- Publication type
Journal Article
- DOI
10.1038/nmeth.1984