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- Title
Yeast one-hybrid assays for gene-centered human gene regulatory network mapping.
- Authors
Reece-Hoyes, John S; Barutcu, A Rasim; McCord, Rachel Patton; Jeong, Jun Seop; Jiang, Lizhi; MacWilliams, Andrew; Yang, Xinping; Salehi-Ashtiani, Kourosh; Hill, David E; Blackshaw, Seth; Zhu, Heng; Dekker, Job; Walhout, Albertha J M
- Abstract
Gateway-compatible yeast one-hybrid (Y1H) assays provide a convenient gene-centered (DNA to protein) approach to identify transcription factors that can bind a DNA sequence of interest. We present Y1H resources, including clones for 988 of 1,434 (69%) predicted human transcription factors, that can be used to detect both known and new interactions between human DNA regions and transcription factors.
- Publication
Nature methods, 2011, Vol 8, Issue 12, p1050
- ISSN
1548-7105
- Publication type
Journal Article
- DOI
10.1038/nmeth.1764