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- Title
Dendritic cell subsets in primary and secondary T cell responses at body surfaces.
- Authors
Heath, William R; Carbone, Francis R
- Abstract
We examine the role of dendritic cells subsets in immunity to peripheral infections, with emphasis on the differences in the regulation of primary and secondary T cell responses to viruses. Our major focus is on new developments in the understanding of immunity to infections of the skin and lung, which are crucial entry points for a variety of infectious pathogens. Initially we describe a diverse network of dendritic cell subsets, but then we argue for a more generalized model of reduced complexity.
- Publication
Nature immunology, 2009, Vol 10, Issue 12, p1237
- ISSN
1529-2916
- Publication type
Journal Article
- DOI
10.1038/ni.1822