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- Title
Alternative splicing and genome complexity.
- Authors
Brett, David; Pospisil, Heike; Valcárcel, Juan; Reich, Jens; Bork, Peer
- Abstract
Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. It has recently been proposed as a mechanism by which higher-order diversity is generated. Here we show, using large-scale expressed sequence tag (EST) analysis, that among seven different eukaryotes the amount of alternative splicing is comparable, with no large differences between humans and other animals.
- Publication
Nature genetics, 2002, Vol 30, Issue 1, p29
- ISSN
1061-4036
- Publication type
Journal Article
- DOI
10.1038/ng803