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- Title
Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1.
- Authors
Zheng, Zuyu; Guo, Yongxia; Novák, Ondřej; Dai, Xinhua; Zhao, Yunde; Ljung, Karin; Noel, Joseph P; Chory, Joanne
- Abstract
We identify an Arabidopsis pyridoxal-phosphate-dependent aminotransferase, VAS1, whose loss-of-function simultaneously increases amounts of the phytohormone auxin and the ethylene precursor 1-aminocyclopropane-1-carboxylate. VAS1 uses the ethylene biosynthetic intermediate methionine as an amino donor and the auxin biosynthetic intermediate indole-3-pyruvic acid as an amino acceptor to produce L-tryptophan and 2-oxo-4-methylthiobutyric acid. Our data indicate that VAS1 serves key roles in coordinating the amounts of these two vital hormones.
- Publication
Nature chemical biology, 2013, Vol 9, Issue 4, p244
- ISSN
1552-4469
- Publication type
Journal Article
- DOI
10.1038/nchembio.1178