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- Title
Defining an epigenetic code.
- Authors
Turner, Bryan M
- Abstract
The nucleosome surface is decorated with an array of enzyme-catalysed modifications on histone tails. These modifications have well-defined roles in a variety of ongoing chromatin functions, often by acting as receptors for non-histone proteins, but their longer-term effects are less clear. Here, an attempt is made to define how histone modifications operate as part of a predictive and heritable epigenetic code that specifies patterns of gene expression through differentiation and development.
- Publication
Nature cell biology, 2007, Vol 9, Issue 1, p2
- ISSN
1465-7392
- Publication type
Journal Article
- DOI
10.1038/ncb0107-2