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- Title
Folate fortification of rice by metabolic engineering.
- Authors
Storozhenko, Sergei; De Brouwer, Veerle; Volckaert, Maarten; Navarrete, Oscar; Blancquaert, Dieter; Zhang, Guo-Fang; Lambert, Willy; Van Der Straeten, Dominique
- Abstract
Rice, the world's major staple crop, is a poor source of essential micronutrients, including folates (vitamin B9). We report folate biofortification of rice seeds achieved by overexpressing two Arabidopsis thaliana genes of the pterin and para-aminobenzoate branches of the folate biosynthetic pathway from a single locus. We obtained a maximal enhancement as high as 100 times above wild type, with 100 g of polished raw grains containing up to four times the adult daily folate requirement.
- Publication
Nature biotechnology, 2007, Vol 25, Issue 11, p1277
- ISSN
1087-0156
- Publication type
Journal Article
- DOI
10.1038/nbt1351