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- Title
Deep homology and the origins of evolutionary novelty.
- Authors
Shubin, Neil; Tabin, Cliff; Carroll, Sean
- Abstract
Do new anatomical structures arise de novo, or do they evolve from pre-existing structures? Advances in developmental genetics, palaeontology and evolutionary developmental biology have recently shed light on the origins of some of the structures that most intrigued Charles Darwin, including animal eyes, tetrapod limbs and giant beetle horns. In each case, structures arose by the modification of pre-existing genetic regulatory circuits established in early metazoans. The deep homology of generative processes and cell-type specification mechanisms in animal development has provided the foundation for the independent evolution of a great variety of structures.
- Publication
Nature, 2009, Vol 457, Issue 7231, p818
- ISSN
1476-4687
- Publication type
Journal Article
- DOI
10.1038/nature07891